Irritants that can trigger vasomotor rhinitis include cigarette
smoke, strong odors and fumes, including perfume, hair spray, other
cosmetics, laundry detergents, cleaning solutions, pool chlorine, car
exhaust and other air pollution. Other irritants are spices used in
cooking, alcoholic beverages (particularly beer and wine), aspirin and
certain blood pressure medications. Some people are very sensitive to
abrupt changes in weather or temperature. Skiers often develop a runny
nose, but in some people any cold exposure may cause a runny nose.
Others start sneezing when leaving a cold, air-conditioned room. These
agents are not allergens, do not induce formation of allergic
antibodies, and do not produce positive skin test reactions.
Occasionally, one or two positive skin tests may be observed, but they
do not match with the history and are not relevant or significant.
The cause of vasomotor rhinitis is not well understood. In a
sufficiently high concentration, many odors will cause nasal irritation
in almost anyone. Some people are unusually sensitive to irritation and
will have significant nasal symptoms even when exposed to low
concentrations of irritants. Thus, vasomotor rhinitis seems to be an
exaggeration of the normal nasal response to irritation, occurring at
levels of exposure that don't bother most people. It occurs more often
in smokers and older individuals.
As is the case with allergic rhinitis, vasomotor rhinitis often can't
be cured. Fortunately, symptoms can be kept under control by limiting
exposure to substances that cause symptoms and by taking medication when
needed. Patients with vasomotor rhinitis should not smoke or permit
smoking in their homes.
Dryness of the nasal tissues can be a normal effect of aging, or a
characteristic of a nasal condition associated with a foul smelling
nasal discharge. Rhinitis also can be a feature of endocrine disease,
like hypothyroidism, or can occur during pregnancy. Rhinitis can be made
worse or even improved during pregnancy. Alcoholic beverages can cause
the blood vessels in the nose to enlarge temporarily and produce
significant nasal congestion.
How Do You Know What Kind of Rhinitis You Have?
Consult your physician. Sometimes several conditions can coexist in
the same person. In a single individual, allergic rhinitis could be
complicated by vasomotor rhinitis, septal deviation (curvature of the
bone separating the two sides of the nose) or nasal polyps. Use of spray
decongestants for chronic sinusitis, septal deviation or vasomotor
rhinitis may cause rhinitis medicamentosa. Any of these conditions will
be made worse by catching a cold. Nasal symptoms caused by more than one
problem can be difficult to treat, often requiring the cooperation of an
allergist-immunologist and an otolaryngologist (a physician specializing
in the ear, nose and throat).
Rhinitis
Allergies,
including allergic rhinitis, affect an estimated 40 million to 50
million people in the United States. Some allergies may interfere with
day-to-day activities or lessen the quality of life.
The allergist-immunologist, with his or her specialized training and
expertise in managing allergies, allergic rhinitis and asthma, can
develop a treatment plan for your individual condition. The goal will be
to enable you to lead a life that is as normal and symptom-free as
possible.
What Is Rhinitis?
Rhinitis is a term describing the symptoms produced by nasal
irritation or inflammation. Symptoms of rhinitis include runny nose,
itching, sneezing and stuffy nose due to blockage or congestion. These
symptoms are the nose's natural response to inflammation and irritation,
and they are often associated with itching of the eyes.
Arbitrarily, rhinitis lasting less than six weeks is called acute
rhinitis, and persistent symptoms are called chronic rhinitis. Acute
rhinitis is usually caused by infections or chemical irritation. Chronic
rhinitis may be caused by allergy or a variety of other factors.
The nose normally produces mucus, which traps substances like dust,
pollen, pollution and germs, such as bacteria and viruses. Mucus flows
from the front of the nose and drains down the back of the throat. When
mucus production is excessive, it can flow from the front, as a runny
nose, or become noticeable from the back, as post-nasal drip. Nasal
mucus, normally a thin, clear liquid, can become thick or colored,
perhaps due to dryness, infection or pollution. When post-nasal drip is
excessive, thick or contains irritating substances, cough is the natural
response for clearing the throat.
Itching and sneezing are also natural responses to irritation caused
by allergic reactions, chemical exposures including cigarette smoke,
temperature changes, infections and other factors.
The nasal tissues congest and decongest periodically. In most people,
nasal congestion switches back and forth from side to side of the nose
in a cycle several hours long. Some people, especially those with narrow
nasal passages, notice this nasal cycle more than others. Strenuous
exercise or changes in head position can affect nasal congestion. Severe
congestion can result in facial pressure and pain, as well as dark
circles under the eyes.
What Is Sinusitis?
Sinusitis is inflammation or infection of any of the four groups of
sinus cavities in the skull, which open into the nasal passages.
Sinusitis is not the same as rhinitis, although the two may be
associated, and their symptoms may be similar. The terms "sinus
trouble" or "sinus congestion" are sometimes wrongly used
to mean congestion of the nasal passage itself. Most cases of nasal
congestion, though, are not associated with sinusitis.
What Is Allergic Rhinitis?
Known to most people as hay fever, allergic rhinitis is a very common
medical problem affecting more than 15 percent of the population, both
adults and children.
Allergic rhinitis takes two different forms: seasonal and perennial.
Symptoms of seasonal allergic rhinitis occur in spring, summer and/or
early fall and are usually caused by allergic sensitivity to pollens
from trees, grasses or weeds, or to airborne mold spores. Other people
experience symptoms year-round, a condition called "perennial
allergic rhinitis". It's generally caused by sensitivity to house
dust mites, animal dander and/or mold spores. Underlying or hidden food
allergies are sometimes a cause of perennial nasal symptoms.
Some people may experience both types of rhinitis, with perennial
symptoms worsening during specific pollen seasons. As will be discussed
later, there are also other causes for rhinitis.
Is Allergic Rhinitis Ever the Cause of Other Problems?
Some known complications include ear infections, sinusitis, recurrent
sore throats, cough, headache, altered sleep patterns, fatigue,
irritability and poor school performance. Occasionally, children may
develop altered facial growth and orthodontic problems. Allergy
treatment can eliminate or alleviate most of these problems.
Are All Cases of Rhinitis Caused by Allergies?
Rhinitis may result from many causes other than allergy. Not all
rhinitis symptoms are the result of allergies. Below are listed the
three most common causes of rhinitis with some of their characteristics.
The most common condition causing rhinitis is the common cold, an
example of infectious rhinitis. Most infections are relatively
short-lived, with symptoms improving at three to seven days. Colds can
be caused by any one of more than 200 viruses. Children, particularly
young children in school or day care centers, may have from eight to 12
colds each year. Fortunately, the frequency of colds lessens after
immunity has been produced from exposure to many viruses.
Colds usually begin with a sensation of congestion, rapidly followed
by runny nose and sneezing. Over the next few days, congestion becomes
more prominent, the nasal mucus may become colored, and there may be a
slight fever and cough. Cold symptoms resolve within a couple of weeks,
although a cough may sometimes persist. Cold symptoms that last longer
may be due to other causes, such as chronic rhinitis or sinusitis.
What are other causes of rhinitis? Not all symptoms in the nasal
passage are caused by allergy or infection. Similar symptoms can be
caused by mechanical blockage, use of certain medications, irritants,
temperature changes or other physical factors. Rhinitis can also be a
feature of other diseases and medical conditions.
Drug-induced nasal congestion can be caused by birth control pills
and other female hormone preparations, certain blood pressure
medications, and prolonged use of decongestant nasal sprays.
Decongestant nasal sprays work quickly and effectively, but they
alter how the nasal passages normally work. After a few weeks of use,
nasal tissues swell after the medication wears off. The only thing that
seems to relieve the obstruction is more of the medicine, and the
medication's effect lasts shorter lengths of time. Permanent damage to
the nasal tissues may result. Consultation with a physician to "get
off" the medication is often necessary.
Cocaine also alters how the nasal passages normally work, causing a
condition identical to, or even more severe than that produced by
decongestant nasal sprays. If you use cocaine, it is important to tell
your physician so that appropriate therapy can be prescribed.
Irritant rhinitis, or "vasomotor rhinitis" describes a
group of other causes of rhinitis, with symptoms not caused by infection
or allergy. Many people have recurrent or chronic nasal congestion,
excess mucus production, itching, and other nasal symptoms similar to
those of allergic rhinitis, but the disorder is not caused by allergy.
How Is Allergic Rhinitis Diagnosed?
Your allergist-immunologist may begin by taking a detailed history,
looking for clues in your lifestyle that will help pinpoint the cause of
your symptoms. You'll be asked about your work and home environments,
your eating habits, your family's medical history, the frequency and
severity of your symptoms, and miscellaneous matters, such as if you
have pets. Then, you may require some tests. Your allergist-immunologist
may employ skin testing, in which small amounts of suspected allergen
are introduced into the skin. Skin-testing is the easiest, most
sensitive and generally least expensive way of making the diagnosis.
Another advantage is that results are available immediately. In rare
cases, it also may be necessary to do a special IgE allergy blood test
for specific allergens.
How Is Rhinitis Treated?
When no specific cure is available, options include ignoring your
symptoms, avoiding or decreasing exposure to irritants or allergens to
the extent practical, and taking medications for symptom relief.
Once allergic rhinitis is diagnosed, treatment options include
avoidance, medication and immunotherapy (allergy shots).
Avoidance - A single ragweed plant may release 1 million
pollen grains in just one day. The pollen from ragweed, grasses and
trees is so small and buoyant that the wind may carry it miles from its
source. Mold spores, which grow outdoors in fields and on dead leaves,
also are everywhere and may outnumber pollen grains in the air even when
the pollen season is at its worst.
While it's difficult to escape pollen and molds, here are some ways
to lessen exposure.
Keep windows closed and use air-conditioning in the summer, if
possible. A HEPA (High Energy Particulate Air) filter or an
electrostatic precipitator may help clean pollen and mold from the
indoor air. Automobile air conditioners help, too.
Don't hang clothing outdoors to dry. Pollen may cling to towels
and sheets.
The outdoor air is most heavily saturated with pollen and mold
between 5 a.m. and 10 a.m., so early morning is a good time to limit
outdoor activities.
Wear a dust mask when mowing the lawn, raking leaves or gardening,
and take appropriate medication beforehand.
Medication - When avoidance measures don't control symptoms,
medication may be the answer. Antihistamines and decongestants are the
most commonly used medications for allergic rhinitis. Other medications,
such as cromolyn (Nasalcrom®), inhibit the release of
chemicals that cause allergic reactions. Nasal corticosteroid sprays
reduce the inflammation from the allergic trigger. Medications help to
alleviate nasal congestion, runny nose, sneezing and itching. They are
available in many forms, including tablets, nasal sprays, eye drops and
liquids. Some medications may cause side effects, so it is best to
consult your allergist-immunologist if there's a problem.
Immunotherapy - Allergen immunotherapy, known as "allergy
shots", may be recommended for persons who don't respond well to
treatment with medications, experience side-effects from medications, or
have allergen exposure that is unavoidable. Immunotherapy can be very
effective in controlling allergic symptoms. Allergy injections are
usually given at variable intervals over a period of three to five
years.
An immunotherapy treatment program consists of injections of a
diluted allergy extract, administered frequently in increasing doses
until a maintenance dose is reached. Then, the injection schedule is
changed so that the same dose is given with longer intervals between
injections. Immunotherapy helps the body build resistance to the effects
of the allergen, reduces the intensity of symptoms caused by allergen
exposure, and sometimes can actually make skin test reactions disappear.
As resistance develops, symptoms should improve, but the improvement
from immunotherapy will take several months to occur. Immunotherapy does
not help the symptoms produced by non-allergic rhinitis.
There are many ways of treating allergies, and each person's
treatment must be individualized based on the frequency, severity and
duration of symptoms and on the degree of allergic sensitivity. If you
have more questions, your allergist-immunologist will be happy to answer
them.
About Antihistamines
Antihistamines are the most inexpensive and commonly used treatment
for rhinitis. These medications counter the effects of histamine, the
irritating chemical released within your body when an allergic reaction
takes place. Although other chemicals are involved, histamine is
primarily responsible for causing the symptoms.
Antihistamines do not cure, but help relieve: nasal allergy symptoms
such as sneezing, itching and runny nose; eye symptoms such as itching,
burning, tearing and clear discharge; skin conditions such as hives,
eczema, itching and some rashes; and certain other allergic conditions.
There are dozens of different antihistamines and wide variations in
how patients respond to them. Some are available over-the-counter and
others require a prescription.
Generally, they work well, and the prescription products produce only
minor side effects. Some people tend to build up resistance to some
antihistamines over time. This tendency varies widely from individual to
individual. If you find that an antihistamine loses its
"strength," notify your physician, who may then recommend an
antihistamine of a different class or strength. Persons with nasal
dryness or thick nasal mucus should avoid taking antihistamines without
consulting a physician. Contact your physician for advice if an
antihistamine causes drowsiness or other side effects.
Proper Use
Short-acting antihistamines can be taken every four to six hours,
while timed-release antihistamines are taken every 12 to 24 hours. The
short-acting antihistamines are often most helpful taken 30 minutes
before anticipated allergic exposure (picnic during ragweed season).
Timed-release antihistamines are better suited to chronic (long-term)
use for those who need daily medications.
Proper use of these drugs is just as important as their selection.
The most effective way to use them is before symptoms develop. A dose
taken early can eliminate the need for many later doses to reduce
established symptoms. Many times a patient will say that he "took
one, and it didn't work." If he or she had taken the antihistamine
regularly for three to four days, and built up blood levels, it might
have been effective.
Side Effects
The most common side effect is sedation or drowsiness. For this
reason, it is important that you do not drive a car or work with
dangerous machinery the first time you take potentially sedating
antihistamine. You should take the antihistamine for the first time at
home, several hours before bedtime. When you are sure that the medicine
will not cause sedation, you then can take it any time as prescribed
during the day. In persons who experience drowsiness, the sedation
effect usually lessens over time, but there could still be performance
impairment. Some of the newer antihistamines have no drowsiness side
effects.
Another frequently encountered side effect is excessive dryness of
the mouth, nose and eyes. Less common side effects include restlessness,
nervousness, over excitability, insomnia, dizziness, headaches,
euphoria, fainting, visual disturbances, decreased appetite, nausea,
vomiting, abdominal distress, constipation, diarrhea, increased or
decreased urination, high or low blood pressure, nightmares (especially
in children), sore throat, unusual bleeding or bruising, chest tightness
or palpitations. Consult your allergist-immunologist should these
reactions occur.
Alcohol and tranquilizers increase the sedation side effects of
antihistamines.
Important precautions:
Never take anyone else's medication.
Do not use more than one antihistamine at a time, unless
prescribed.
Keep these medications out of the reach of children.
Know the effect of the medication on you before working with heavy
machinery, driving or doing other performance-intensive tasks; some
products can slow your "reaction time."
Follow your physician's instructions.
There have not been enough studies to determine absolute safety of
antihistamines in pregnancy. Again, consult your allergist-immunologist
or obstetrician if antihistamines must be taken.
While antihistamines have been taken safely by millions of people in
the last 50 years, don't take antihistamines before telling your
allergist-immunologist if you are allergic to or intolerant of any
medicine; are pregnant or intend to become pregnant while using this
medication; are breast feeding; have glaucoma or enlarged prostate; or
have any medical illness.
What Other Medications Are Effective in Treating Rhinitis?
Decongestants help relieve the stuffiness and pressure caused
by swollen nasal tissue. They do not contain antihistamines, so they do
not cause antihistamine side effects. They do not relieve the other
symptoms of allergic rhinitis, such as runny nose, post-nasal drip and
sneezing. Decongestants are available as prescription and
non-prescription medications and are often seen in combination with
antihistamines or other medications. It is not uncommon for patients
using decongestants to experience insomnia if taking the medication in
the afternoon or evening. If this occurs, a dose reduction may be
needed.
At times, men with prostate enlargement may encounter urinary
problems while on decongestants. Patients using medications for the
management of emotional or behavioral problems should discuss this with
their physicians before using decongestants. Pregnant patients should
also check with their physician before starting decongestants.
Non-prescription decongestant nasal sprays work within minutes
and last for hours, but should not be used for more than a few days at a
time without a physician's order.
Oral decongestants are found in many over-the-counter and
prescription medications, and may be the treatment of choice for nasal
congestion. They don't cause rhinitis medicamentosa but need to be
avoided by some patients with high blood pressure. If you have high
blood pressure, you should check with your physician before using them.
Non-prescription saline nasal sprays will help counteract
symptoms of dry nasal passages or thick nasal mucus. Unlike decongestant
nose sprays, a saline nose spray can be used as often as needed.
Sometimes, your physician may recommend washing (douching) of the nasal
passage.
Corticosteroids counteract the inflammation caused by the
body's release of allergy-causing substances, as well as that caused by
other non-allergic factors. Thus, they generally work for many causes of
rhinitis symptoms and are sometimes useful for chronic sinusitis.
Corticosteroids are sometimes injected or taken orally but usually on a
short-term basis for extremely severe symptoms. Physicians warn that
injected or oral steroids may produce severe side effects when used for
long periods or used repeatedly and, for this reason, they should be
used with caution. In rhinitis, a corticosteroid is much safer when used
by spraying it into the nose. Side effects are less common but may
include nasal ulceration, nasal fungal infection or bleeding.
Cromolyn is a medication that blocks the body's release of
allergy-causing substances. It does not work in all patients. The full
dosage is four times daily, and improvement may take several weeks to
occur.
Atropine and the related drug ipratropium bromide are
sometimes used to relieve the runny nose of rhinitis; in fact, most
antihistamines have a slight atropine-like effect. Atropine can be taken
orally and as a nasal spray. It is a component of some
antihistamine-decongestant preparations.
Antibiotics are for the treatment of bacterial infections.
They do not affect the course of uncomplicated common colds and are of
no benefit for non-infectious rhinitis, including allergic rhinitis. In
chronic sinusitis, antibiotics may help only temporarily, and surgery
may be needed.
Eye allergy preparations are used when the eyes are affected
by the same allergens that trigger rhinitis, causing redness, watery
eyes and itching. Eye preparations are available as prescription and
non-prescription medications. Check with your physician or pharmacist
about these medications.
Nasal surgery will usually cure or improve symptoms caused by
mechanical blockage or chronic sinusitis not responsive to prolonged
antibiotics and nasal steroid sprays. Stopping the use of offending
medications will cure rhinitis medicamentosa, providing that there is no
underlying disorder.
Check with your physician or pharmacist if you are unsure about a
specific drug or formula.
Medications for the Treatment of Rhinitis
Non-prescription antihistamines
All of the non-prescription antihistamines (combined with decongestants)
are "first generation" antihistamines and generally cause
drowsiness, slowed reaction time and dry mouth in most people.
Many brand name and generic formulas are available without prescription.
If you are in doubt as to whether or not a product contains an
antihistamine, consult your physician or pharmacist.
Prescription Antihistamines
The following medications are "second generation"
antihistamines that do not generally cause the side effects of
"first generation" antihistamines, such as drowsiness, slowed
reaction time and dry mouth.
Allegra®
Claritin®
Zyrtec® *
*Low sedating.
The following contain "first generation" antihistamines
that can cause drowsiness, slowed reaction time and dry mouth.
Prescription Nasal Corticosteroid sprays
These do not contain antihistamines or decongestants.
Beconase® (Pockethaler and Beconase AQ)
Flonase®
Nasacort® (Nasal Inhaler and Nasacort AQ)
Nasalide®
Nasonex®
Rhinocort®
Vancenase® (Pockethaler and Vancenase DS)
What Causes the Sneezing, Itchy Eyes and Other Symptoms?
When a sensitive person inhales an allergen (allergy-causing
substance) like ragweed pollen, the body's immune system reacts
abnormally with the allergen. The allergen binds to allergic antibodies
(immunoglobulin E) that are attached to cells that produce histamine and
other chemicals. The pollen "triggers" these cells in the
nasal membranes, causing them to release histamine and the other
chemicals. Histamine dilates the small blood vessels of the nose and
fluids leak out into the surrounding tissues, causing runny noses,
watery eyes, itching, swelling and other allergy symptoms.
Antibodies circulate in the blood stream, but localize in the tissues
of the nose and in the skin. This makes it possible to show the presence
of these antibodies by skin testing, or less commonly, by a special IgE
allergy blood test. A positive skin test mirrors the type of reaction
going on in the nose.
No Hay, No Fever, so Why "Hay Fever"?
"Hay fever" is a turn-of-the-century term that has come to
describe the symptoms of allergic rhinitis, especially when it occurs in
the late summer. However, the symptoms are not caused by hay (ragweed is
one of the main culprits) and are not accompanied by fever. So, the term
"allergic rhinitis" is more accurate. Similarly, springtime
symptoms are sometimes called "rose fever," but it's just
coincidental that roses are in full-bloom during the grass-pollinating
season. Roses and other sweet-smelling, showy flowers rely on bees, not
the wind, for pollination, so not much of their pollen gets into the air
to cause allergies.
Is There Any Escape?
A common question from allergic rhinitis sufferers is: Can I move
someplace where my allergies will go away? Some allergens are tough to
escape. Ragweed, which affects 75 percent of allergic rhinitis
sufferers, blankets most of the United States. Less ragweed is found in
a band along the West Coast, the southern-most tip of Florida and
northern Maine, but it is still present. Even parts of Alaska and Hawaii
have a little ragweed.
Allergist-immunologists seldom recommend moving to another locale as
a cure for allergies. A move may be of questionable value because a
person may escape one allergy to ragweed, for example, only to develop
sensitivity to grasses or other allergens in the new location. Since
moving can have a disrupting effect on a family financially and
emotionally, relocation should be considered only in an extreme
situation and only after consultation with an allergist-immunologist.